Fitness Landscapes: An Alternative Theory for the Dominance of Mutation

نویسندگان
چکیده

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Fitness landscapes: an alternative theory for the dominance of mutation.

Deleterious mutations tend to be recessive. Several theories, notably those of Fisher (based on selection) and Wright (based on metabolism), have been put forward to explain this pattern. Despite a long-lasting debate, the matter remains unresolved. This debate has focused on the average dominance of mutations. However, we also know very little about the distribution of dominance coefficients a...

متن کامل

Quasispecies theory for multiple-peak fitness landscapes.

We use a path integral representation to solve the Eigen and Crow-Kimura molecular evolution models for the case of multiple fitness peaks with arbitrary fitness and degradation functions. In the general case, we find that the solution to these molecular evolution models can be written as the optimum of a fitness function, with constraints enforced by Lagrange multipliers and with a term accoun...

متن کامل

2-bit Flip Mutation Elementary Fitness Landscapes

Genetic Programming parity with only XOR is not elementary. GP parity can be represented as the sum of k/2 + 1 elementary landscapes. Statistics, including fitness distance correlation (FDC), of Parity’s fitness landscape are calculated. Using Walsh analysis the eigen values and eigenvectors of the Laplacian of the two bit flip fitness landscape are given. Tests support λ/d as a measure of the ...

متن کامل

Dynamic fitness landscapes: Expansions for small mutation rates

We study the evolution of asexual microorganisms with small mutation rate in fluctuating environments, and develop techniques that allow us to expand the formal solution of the evolution equations to first order in the mutation rate. Our method can be applied to both discrete time and continuous time systems. While the behavior of continuous time systems is dominated by the average fitness land...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Genetics

سال: 2011

ISSN: 1943-2631

DOI: 10.1534/genetics.111.132944